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Low Enzymatic Activity Haplotypes of the Human Catechol-O-Methyltransferase Gene: Enrichment for Marker SNPs

Catechol-O-methyltransferase (COMT) is an enzyme that plays a key role in the modulation of catechol-dependent functions such as cognition, cardiovascular function, and pain processing. Three common haplotypes of the human COMT gene, divergent in two synonymous and one nonsynonymous (val (158) met)...

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Detalles Bibliográficos
Autores principales:	Nackley, Andrea G., Shabalina, Svetlana A., Lambert, Jason E., Conrad, Mathew S., Gibson, Dustin G., Spiridonov, Alexey N., Satterfield, Sarah K., Diatchenko, Luda
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664927/ https://www.ncbi.nlm.nih.gov/pubmed/19365560 http://dx.doi.org/10.1371/journal.pone.0005237

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