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Sem1p and Ubp6p orchestrate telomeric silencing by modulating histone H2B ubiquitination and H3 acetylation

Histone covalent modifications and 26S proteasome-mediated proteolysis modulate many regulatory events in eukaryotes. In Saccharomyces cerevisiae, heterochromatin mediates transcriptional silencing at telomeres, HM loci and rDNA array. Here, we show that proteasome-associated Sem1p and its interacti...

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Detalles Bibliográficos
Autores principales:	Qin, Song, Wang, Qien, Ray, Alo, Wani, Gulzar, Zhao, Qun, Bhaumik, Sukesh R., Wani, Altaf A.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665209/ https://www.ncbi.nlm.nih.gov/pubmed/19188254 http://dx.doi.org/10.1093/nar/gkn1049

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