Human DNA polymerase θ possesses 5′-dRP lyase activity and functions in single-nucleotide base excision repair in vitro

DNA polymerase θ (Pol θ) is a low-fidelity DNA polymerase that belongs to the family A polymerases and has been proposed to play a role in somatic hypermutation. Pol θ has the ability to conduct translesion DNA synthesis opposite an AP site or thymine glycol, and it was recently proposed to be invol...

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Detalles Bibliográficos
Autores principales: Prasad, Rajendra, Longley, Matthew J., Sharief, Farida S., Hou, Esther W., Copeland, William C., Wilson, Samuel H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665223/
https://www.ncbi.nlm.nih.gov/pubmed/19188258
http://dx.doi.org/10.1093/nar/gkp035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665223/
https://www.ncbi.nlm.nih.gov/pubmed/19188258
http://dx.doi.org/10.1093/nar/gkp035

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