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Precursor-product discrimination by La protein during tRNA metabolism

La proteins bind pre-tRNAs at their UUU-3'OH ends, facilitating their maturation. While the mechanism by which La binds pre-tRNA 3' trailers is known, the function of the RNA-binding β-sheet surface of RRM1 is unknown. How La dissociates from UUU-3'OH-containing trailers after 3'...

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Detalles Bibliográficos
Autores principales: Bayfield, Mark A., Maraia, Richard J.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666094/
https://www.ncbi.nlm.nih.gov/pubmed/19287396
http://dx.doi.org/10.1038/nsmb.1573

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