A Novel Method for Detection of Phosphorylation in Single Cells by Surface Enhanced Raman Scattering (SERS) using Composite Organic-Inorganic Nanoparticles (COINs)

BACKGROUND: Detection of single cell epitopes has been a mainstay of immunophenotyping for over three decades, primarily using fluorescence techniques for quantitation. Fluorescence has broad overlapping spectra, limiting multiplexing abilities. METHODOLOGY/PRINCIPAL FINDINGS: To expand upon current...

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Detalles Bibliográficos
Autores principales: Shachaf, Catherine M., Elchuri, Sailaja V., Koh, Ai Leen, Zhu, Jing, Nguyen, Lienchi N., Mitchell, Dennis J., Zhang, Jingwu, Swartz, Kenneth B., Sun, Lei, Chan, Selena, Sinclair, Robert, Nolan, Garry P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666268/
https://www.ncbi.nlm.nih.gov/pubmed/19367337
http://dx.doi.org/10.1371/journal.pone.0005206

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