Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture

BACKGROUND: MCF-10A cells are near diploid and normal human mammary epithelial cells. In three-dimensional reconstituted basement membrane culture, they undergo a well-defined program of proliferation, differentiation, and growth arrest, forming acinar structures that recapitulate many aspects of ma...

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Detalles Bibliográficos
Autores principales: Imbalzano, Karen M, Tatarkova, Iva, Imbalzano, Anthony N, Nickerson, Jeffrey A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666639/
https://www.ncbi.nlm.nih.gov/pubmed/19291318
http://dx.doi.org/10.1186/1475-2867-9-7

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