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Role of oxidative stress and intracellular glutathione in the sensitivity to apoptosis induced by proteasome inhibitor in thyroid cancer cells

BACKGROUND: The proteasome inhibitor bortezomib has shown impressive clinical activity alone and in combination with conventional and other novel agents for the treatment of multiple myeloma (MM) and some solid cancers. Although bortezomib is known to be a selective proteasome inhibitor, the downstr...

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Detalles Bibliográficos
Autores principales:	Du, Zhen-Xian, Zhang, Hai-Yan, Meng, Xin, Guan, Yifu, Wang, Hua-Qin
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666756/ https://www.ncbi.nlm.nih.gov/pubmed/19216805 http://dx.doi.org/10.1186/1471-2407-9-56

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