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Characterization of STAT3 activation and expression in canine and human osteosarcoma

BACKGROUND: Dysregulation of signal transducer and activator of transcription 3 (STAT3) has been implicated as a key participant in tumor cell survival, proliferation, and metastasis and is often correlated with a more malignant tumor phenotype. STAT3 phosphorylation has been demonstrated in a subse...

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Detalles Bibliográficos
Autores principales: Fossey, Stacey L, Liao, Albert T, McCleese, Jennifer K, Bear, Misty D, Lin, Jiayuh, Li, Pui-Kai, Kisseberth, William C, London, Cheryl A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666757/
https://www.ncbi.nlm.nih.gov/pubmed/19284568
http://dx.doi.org/10.1186/1471-2407-9-81