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Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation in colon cancer

BACKGROUND: UbcH10 participates in proper metaphase to anaphase transition, and abrogation of UbcH10 results in the premature separation of sister chromatids. To assess the potential role of UbcH10 in colon cancer progression, we analyzed the clinicopathological relevance of UbcH10 in colon cancer....

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Detalles Bibliográficos
Autores principales: Fujita, Takeo, Ikeda, Hirokuni, Taira, Naruto, Hatoh, Shinji, Naito, Minoru, Doihara, Hiroyoshi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666760/
https://www.ncbi.nlm.nih.gov/pubmed/19302711
http://dx.doi.org/10.1186/1471-2407-9-87