Effects of CpG Methylation on Recognition of DNA by the Tumour Suppressor p53

Methylation of DNA is one of the mechanisms controlling the expression landscape of the genome. Its pattern is altered in cancer and often results in the hypermethylation of the promoter regions and abnormal expression of tumour suppressor genes. Methylation of CpG dinucleotides located in the bindi...

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Detalles Bibliográficos
Autores principales: Petrovich, Miriana, Veprintsev, Dmitry B.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666794/
https://www.ncbi.nlm.nih.gov/pubmed/19084536
http://dx.doi.org/10.1016/j.jmb.2008.11.054

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