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Predicting the binding preference of transcription factors to individual DNA k-mers
Motivation: Recognition of specific DNA sequences is a central mechanism by which transcription factors (TFs) control gene expression. Many TF-binding preferences, however, are unknown or poorly characterized, in part due to the difficulty associated with determining their specificity experimentally...
Autores principales: | Alleyne, Trevis M., Peña-Castillo, Lourdes, Badis, Gwenael, Talukder, Shaheynoor, Berger, Michael F., Gehrke, Andrew R., Philippakis, Anthony A., Bulyk, Martha L., Morris, Quaid D., Hughes, Timothy R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666811/ https://www.ncbi.nlm.nih.gov/pubmed/19088121 http://dx.doi.org/10.1093/bioinformatics/btn645 |
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