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Kinase Domain Insertions Define Distinct Roles of CLK Kinases in SR Protein Phosphorylation

Splicing requires reversible phosphorylation of serine/arginine-rich (SR) proteins, which direct splice site selection in eukaryotic mRNA. These phosphorylation events are dependent on SR protein (SRPK) and cdc2-like kinase (CLK) families. SRPK1 phosphorylation of splicing factors is restricted by a...

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Detalles Bibliográficos
Autores principales:	Bullock, Alex N., Das, Sanjan, Debreczeni, Judit É., Rellos, Peter, Fedorov, Oleg, Niesen, Frank H., Guo, Kunde, Papagrigoriou, Evangelos, Amos, Ann L., Cho, Suhyung, Turk, Benjamin E., Ghosh, Gourisankar, Knapp, Stefan
Formato:	Texto
Lenguaje:	English
Publicado:	Cell Press 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667211/ https://www.ncbi.nlm.nih.gov/pubmed/19278650 http://dx.doi.org/10.1016/j.str.2008.12.023

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