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Chemically-Induced RAT Mesenchymal Stem Cells Adopt Molecular Properties of Neuronal-Like Cells but Do Not Have Basic Neuronal Functional Properties

Induction of adult rat bone marrow mesenchymal stem cells (MSC) by means of chemical compounds (β-mercaptoethanol, dimethyl sulfoxide and butylated hydroxyanizole) has been proposed to lead to neuronal transdifferentiation, and this protocol has been broadly used by several laboratories worldwide. O...

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Detalles Bibliográficos
Autores principales: Barnabé, Gabriela F., Schwindt, Telma T., Calcagnotto, Maria E., Motta, Fabiana L., Martinez, Gilberto, de Oliveira, Allan C., Keim, Leda M. N., D'Almeida, Vânia, Mendez-Otero, Rosália, Mello, Luiz E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667250/
https://www.ncbi.nlm.nih.gov/pubmed/19370156
http://dx.doi.org/10.1371/journal.pone.0005222