Mixed Candida albicans strain populations in colonized and infected mucosal tissues

Multilocus sequence typing of six Candida albicans colonies from primary isolation plates revealed instances of colony-to-colony microvariation and carriage of two strain types in single oropharyngeal and vaginal samples. Higher rates of colony variation in commensal samples suggest selection of typ...

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Detalles Bibliográficos
Autores principales: Jacobsen, Mette D, Duncan, Amanda D, Bain, Judith, Johnson, Elizabeth M, Naglik, Julian R, Shaw, Duncan J, Gow, Neil AR, Odds, Frank C
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667310/
https://www.ncbi.nlm.nih.gov/pubmed/18795958
http://dx.doi.org/10.1111/j.1567-1364.2008.00438.x
Descripción
Sumario:Multilocus sequence typing of six Candida albicans colonies from primary isolation plates revealed instances of colony-to-colony microvariation and carriage of two strain types in single oropharyngeal and vaginal samples. Higher rates of colony variation in commensal samples suggest selection of types from mixed populations either in the shift to pathogenicity or the response to antifungal treatment.

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