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Obligatory role for phosphatidylinositol 4,5-bisphosphate in activation of native TRPC1 store-operated channels in vascular myocytes

In the present study the effect of phosphatidylinositol 4,5-bisphosphate (PIP(2)) was studied on a native TRPC1 store-operated channel (SOC) in freshly dispersed rabbit portal vein myocytes. Application of diC8-PIP(2), a water soluble form of PIP(2), to quiescent inside-out patches evoked single cha...

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Detalles Bibliográficos
Autores principales: Saleh, Sohag N, Albert, Anthony P, Large, William A
Formato: Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667327/
https://www.ncbi.nlm.nih.gov/pubmed/19047197
http://dx.doi.org/10.1113/jphysiol.2008.166678