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Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy
BACKGROUND: Neuropathic pain caused by peripheral nerve injury is a chronic disorder that represents a significant clinical challenge because the pathological mechanisms have not been fully elucidated. Several studies have suggested the involvement of various sodium channels, including tetrodotoxin-...
Autores principales: | Thakor, Devang Kashyap, Lin, Audrey, Matsuka, Yoshizo, Meyer, Edward M, Ruangsri, Supanigar, Nishimura, Ichiro, Spigelman, Igor |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667430/ https://www.ncbi.nlm.nih.gov/pubmed/19320998 http://dx.doi.org/10.1186/1744-8069-5-14 |
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