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Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy

BACKGROUND: Neuropathic pain caused by peripheral nerve injury is a chronic disorder that represents a significant clinical challenge because the pathological mechanisms have not been fully elucidated. Several studies have suggested the involvement of various sodium channels, including tetrodotoxin-...

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Detalles Bibliográficos
Autores principales: Thakor, Devang Kashyap, Lin, Audrey, Matsuka, Yoshizo, Meyer, Edward M, Ruangsri, Supanigar, Nishimura, Ichiro, Spigelman, Igor
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667430/
https://www.ncbi.nlm.nih.gov/pubmed/19320998
http://dx.doi.org/10.1186/1744-8069-5-14

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