Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients

BACKGROUND: Assessment of T-cell diversity, besides giving insights about the molecular basis of tumor antigen recognition, has clinical implications since it provides criteria for evaluating antigen-specific T cells clinically relevant for spontaneous and vaccine-induced anti-tumor activity. Melan-...

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Detalles Bibliográficos
Autores principales: Serana, Federico, Sottini, Alessandra, Caimi, Luigi, Palermo, Belinda, Natali, Pier Giorgio, Nisticò, Paola, Imberti, Luisa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667493/
https://www.ncbi.nlm.nih.gov/pubmed/19317896
http://dx.doi.org/10.1186/1479-5876-7-21

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