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The Yeast PNC1 Longevity Gene Is Up-Regulated by mRNA Mistranslation
Translation fidelity is critical for protein synthesis and to ensure correct cell functioning. Mutations in the protein synthesis machinery or environmental factors that increase synthesis of mistranslated proteins result in cell death and degeneration and are associated with neurodegenerative disea...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667667/ https://www.ncbi.nlm.nih.gov/pubmed/19381334 http://dx.doi.org/10.1371/journal.pone.0005212 |