Cargando…

Targeting Angiogenesis-Dependent Calcified Neoplasms Using Combined Polymer Therapeutics

BACKGROUND: There is an immense clinical need for novel therapeutics for the treatment of angiogenesis-dependent calcified neoplasms such as osteosarcomas and bone metastases. We developed a new therapeutic strategy to target bone metastases and calcified neoplasms using combined polymer-bound angio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Segal, Ehud, Pan, Huaizhong, Ofek, Paula, Udagawa, Taturo, Kopečková, Pavla, Kopeček, Jindřich, Satchi-Fainaro, Ronit
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667669/ https://www.ncbi.nlm.nih.gov/pubmed/19381291 http://dx.doi.org/10.1371/journal.pone.0005233

Ejemplares similares

Combination Chemotherapy and Photodynamic Therapy with Fab′ Fragment Targeted HPMA Copolymer Conjugates in Human Ovarian Carcinoma Cells
por: Hongrapipat, Jarunee, et al.
Publicado: (2008)

Prospective Identification of Glioblastoma Cells Generating Dormant Tumors
por: Satchi-Fainaro, Ronit, et al.
Publicado: (2012)

Sulfonated Amphiphilic Poly(α)glutamate Amine—A Potential siRNA Nanocarrier for the Treatment of Both Chemo-Sensitive and Chemo-Resistant Glioblastoma Tumors
por: Krivitsky, Adva, et al.
Publicado: (2021)

Restoring the oncosuppressor activity of microRNA-34a in glioblastoma using a polyglycerol-based polyplex
por: Ofek, Paula, et al.
Publicado: (2016)

Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer
por: Gibori, Hadas, et al.
Publicado: (2018)

Light emission enhancement by supramolecular complexation of chemiluminescence probes designed for bioimaging
por: Gnaim, Samer, et al.
Publicado: (2019)

Co-targeting the tumor endothelium and P-selectin-expressing glioblastoma cells leads to a remarkable therapeutic outcome
por: Ferber, Shiran, et al.
Publicado: (2017)

Bone-Targeted Acid-Sensitive Doxorubicin Conjugate Micelles as Potential Osteosarcoma Therapeutics
por: Low, Stewart A., et al.
Publicado: (2014)

Molecular Weight-Dependent Activity of Aminated Poly(α)glutamates as siRNA Nanocarriers
por: Krivitsky, Adva, et al.
Publicado: (2018)

Porphyrin as a versatile visible-light-activatable organic/metal hybrid photoremovable protecting group
por: Sekhar, Adiki Raja, et al.
Publicado: (2022)

Intratendinous Calcified Chondroid Mesenchymal Neoplasm: A Case Report
por: Warburton, Christopher, et al.
Publicado: (2023)

Immune-mediated approaches against COVID-19
por: Florindo, Helena F., et al.
Publicado: (2020)

Bone metastasis is associated with acquisition of mesenchymal phenotype and immune suppression in a model of spontaneous breast cancer metastasis
por: Monteran, Lea, et al.
Publicado: (2020)

Current hurdles to the translation of nanomedicines from bench to the clinic
por: Đorđević, Snežana, et al.
Publicado: (2021)

Development of Chitosan Particles Loaded with siRNA for Cystatin C to Control Intracellular Drug-Resistant Mycobacterium tuberculosis
por: Pires, David, et al.
Publicado: (2023)

P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression
por: Yeini, Eilam, et al.
Publicado: (2021)

MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression
por: Pozzi, Sabina, et al.
Publicado: (2022)

HPMA Copolymer CXCR4 Antagonist Conjugates Substantially Inhibited the Migration of Prostate Cancer Cells
por: Peng, Zheng-Hong, et al.
Publicado: (2014)

PDEPT: polymer-directed enzyme prodrug therapy
por: Satchi, R, et al.
Publicado: (2001)

Polyglutamate-based nanoconjugates for image-guided surgery and post-operative melanoma metastases prevention
por: Epshtein, Yana, et al.
Publicado: (2022)

Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. II. Evaluation of daunomycin conjugates in vivo against L1210 leukaemia.
por: Duncan, R., et al.
Publicado: (1988)

Therapeutic targeting of PD-1/PD-L1 blockade by novel small-molecule inhibitors recruits cytotoxic T cells into solid tumor microenvironment
por: Acúrcio, Rita C., et al.
Publicado: (2022)

Microengineered perfusable 3D-bioprinted glioblastoma model for in vivo mimicry of tumor microenvironment
por: Neufeld, Lena, et al.
Publicado: (2021)

Lomustine Nanoparticles Enable Both Bone Marrow Sparing and High Brain Drug Levels – A Strategy for Brain Cancer Treatments
por: Fisusi, Funmilola A., et al.
Publicado: (2016)

Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome
por: Shaashua, Lee, et al.
Publicado: (2020)

Publisher Correction: Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome
por: Shaashua, Lee, et al.
Publicado: (2020)

Angiogenesis in myeloproliferative neoplasms, new markers and future directions
por: Medinger, Michael, et al.
Publicado: (2014)

The “Hoover” (vacuum cleaner) technique for calcifying tendonitis deposits excision and removal of the calcific debris
por: Ehud, Atoun, et al.
Publicado: (2012)

Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. I. Evaluation of daunomycin and puromycin conjugates in vitro.
por: Duncan, R., et al.
Publicado: (1987)

Are calcifying microvesicles another analogous substructure of calcifying nanoparticles?
por: Atughonu, Trueman C, et al.
Publicado: (2013)

Optimal Electrode Selection for Electrical Resistance Tomography in Carbon Fiber Reinforced Polymer Composites
por: Escalona Galvis, Luis Waldo, et al.
Publicado: (2017)

Calcified tissues : proceedings of the third European Symposium on Calcified Tissues
Publicado: (1965)

Control of T lymphocyte morphology by the GTPase Rho
por: Woodside, Darren G, et al.
Publicado: (2003)

Meningioangiomatosis Combined with Calcifying Pseudoneoplasms of Neuraxis
por: Sun, Xiangyu, et al.
Publicado: (2023)

Calcified Atherosclerosis and Cancer
por: Elkeles, A.
Publicado: (1959)

Angioléiomyome calcifié plantaire
por: Lemtibbet, Sanaa, et al.
Publicado: (2013)

Odonto calcifying cyst
por: Aswath, Nalini, et al.
Publicado: (2013)

Multiple calcified nodules
por: Marchiori, Edson, et al.
Publicado: (2016)

Calcifying pseudoneoplasm of the neuraxis
por: Pithon, Rafaela Fonseca Albuquerque, et al.
Publicado: (2019)

Calcified metastases of teratoma
por: Souza, Luciana Volpon Soares, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_i92odqf1bbt4i7h0hcqf4b6le7