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Virus free induction of pluripotency and subsequent excision of reprogramming factors

Reprogramming of somatic cells to pluripotency, thereby creating induced pluripotent stem (iPS) cells, promises to transform regenerative medicine. Most instances of direct reprogramming have been achieved by forced expression of defined factors using multiple viral vectors1-7. However, such iPS cel...

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Detalles Bibliográficos
Autores principales: Kaji, Keisuke, Norrby, Katherine, Paca, Agnieszka, Mileikovsky, Maria, Mohseni, Paria, Woltjen, Knut
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667910/
https://www.ncbi.nlm.nih.gov/pubmed/19252477
http://dx.doi.org/10.1038/nature07864

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