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Parasite-Dependent Expansion of TNF Receptor II–Positive Regulatory T Cells with Enhanced Suppressive Activity in Adults with Severe Malaria

Severe Plasmodium falciparum malaria is a major cause of global mortality, yet the immunological factors underlying progression to severe disease remain unclear. CD4(+)CD25(+) regulatory T cells (Treg cells) are associated with impaired T cell control of Plasmodium spp infection. We investigated the...

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Detalles Bibliográficos
Autores principales: Minigo, Gabriela, Woodberry, Tonia, Piera, Kim A., Salwati, Ervi, Tjitra, Emiliana, Kenangalem, Enny, Price, Ric N., Engwerda, Christian R., Anstey, Nicholas M., Plebanski, Magdalena
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668192/
https://www.ncbi.nlm.nih.gov/pubmed/19390618
http://dx.doi.org/10.1371/journal.ppat.1000402