Cargando…

Polo-Like Kinase-1 Controls Aurora A Destruction by Activating APC/C-Cdh1

Polo-like kinase-1 (Plk1) is activated before mitosis by Aurora A and its cofactor Bora. In mitosis, Bora is degraded in a manner dependent on Plk1 kinase activity and the E3 ubiquitin ligase SCF-βTrCP. Here, we show that Plk1 is also required for the timely destruction of its activator Aurora A in...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Leuken, Renske, Clijsters, Linda, van Zon, Wouter, Lim, Dan, Yao, XueBiao, Wolthuis, Rob M. F., Yaffe, Michael B., Medema, René H., van Vugt, Marcel A. T. M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668763/ https://www.ncbi.nlm.nih.gov/pubmed/19390576 http://dx.doi.org/10.1371/journal.pone.0005282

Ejemplares similares

The spindle checkpoint, APC/C(Cdc20), and APC/C(Cdh1) play distinct roles in connecting mitosis to S phase
por: Clijsters, Linda, et al.
Publicado: (2013)

The APC/C recruits cyclin B1–Cdk1–Cks in prometaphase before D box recognition to control mitotic exit
por: van Zon, Wouter, et al.
Publicado: (2010)

Controlling the response to DNA damage by the APC/C-Cdh1
por: de Boer, H. Rudolf, et al.
Publicado: (2015)

Erratum to: Controlling the response to DNA damage by the APC/C-Cdh1
por: de Boer, H. Rudolf, et al.
Publicado: (2016)

APC(CDH1) Targets MgcRacGAP for Destruction in the Late M Phase
por: Nishimura, Koutarou, et al.
Publicado: (2013)

MASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C
por: Voets, Erik, et al.
Publicado: (2015)

Correction: APC(CDH1) Targets MgcRacGAP for Destruction in the Late M Phase
Publicado: (2014)

Polo meets the APC
por: Wells, William A.
Publicado: (2002)

Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor
por: da Fonseca, Paula C.A., et al.
Publicado: (2010)

An APC/C-Cdh1 Biosensor Reveals the Dynamics of Cdh1 Inactivation at the G1/S Transition
por: Ondracka, Andrej, et al.
Publicado: (2016)

Combined Inactivation of Pocket Proteins and APC/C(Cdh1) by Cdk4/6 Controls Recovery from DNA Damage in G1 Phase
por: Shaltiel, Indra A., et al.
Publicado: (2021)

The function of APC/C(Cdh1 )in cell cycle and beyond
por: Li, Min, et al.
Publicado: (2009)

Damaged DNA-binding Protein 1 (DDB1) Interacts with Cdh1 and Modulates the Function of APC/C(Cdh1)
por: Lv, Xiao-Bin, et al.
Publicado: (2010)

Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora
por: Bruinsma, W, et al.
Publicado: (2017)

Uncovering the role of APC-Cdh1 in generating the dynamics of S-phase onset
por: Yuan, Xi, et al.
Publicado: (2014)

Regulation of APC/C-Cdh1 and Its Function in Neuronal Survival
por: Almeida, Angeles
Publicado: (2012)

Cyclin B1–Cdk1 Activation Continues after Centrosome Separation to Control Mitotic Progression
por: Lindqvist, Arne, et al.
Publicado: (2007)

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1
por: Gao, Daming, et al.
Publicado: (2009)

APC/C-Cdh1-targeted substrates as potential therapies for Alzheimer’s disease
por: Lapresa, Rebeca, et al.
Publicado: (2022)

Regulation of mitochondrial morphology by APC/C(Cdh1)-mediated control of Drp1 stability
por: Horn, Sarah R., et al.
Publicado: (2011)

A Cdh1–FoxM1–Apc axis controls muscle development and regeneration
por: Chen, Zhe, et al.
Publicado: (2020)

Co-inhibition of polo-like kinase 1 and Aurora kinases promotes mitotic catastrophe
por: Li, Jingjing, et al.
Publicado: (2015)

Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1)
por: Keck, Jamie M., et al.
Publicado: (2007)

APC/C-Cdh1-dependent anaphase and telophase progression during mitotic slippage
por: Toda, Kazuhiro, et al.
Publicado: (2012)

The ubiquitin ligase APC/C(Cdh1) puts the brakes on DNA-end resection
por: Lafranchi, Lorenzo, et al.
Publicado: (2015)

Insights into Degron Recognition by APC/C Coactivators from the Structure of an Acm1-Cdh1 Complex
por: He, Jun, et al.
Publicado: (2013)

APC(cdh1) Mediates Degradation of the Oncogenic Rho-GEF Ect2 after Mitosis
por: Liot, Caroline, et al.
Publicado: (2011)

Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit
por: Meghini, Francesco, et al.
Publicado: (2016)

The Role of the APC/C and Its Coactivators Cdh1 and Cdc20 in Cancer Development and Therapy
por: Greil, Christine, et al.
Publicado: (2022)

APC/C(Cdh1)-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage
por: Cotto-Rios, Xiomaris M., et al.
Publicado: (2011)

γ-Tubulin plays a key role in inactivating APC/C(Cdh1) at the G(1)–S boundary
por: Edgerton-Morgan, Heather, et al.
Publicado: (2012)

Human KIAA1018/FAN1 nuclease is a new mitotic substrate of APC/C(Cdh1)
por: Lai, Fenju, et al.
Publicado: (2012)

Substrate binding on the APC/C occurs between the co-activator CDH1 and the processivity factor DOC1
por: Buschhorn, Bettina A., et al.
Publicado: (2010)

Dual control by Cdk1 phosphorylation of the budding yeast APC/C ubiquitin ligase activator Cdh1
por: Höckner, Sebastian, et al.
Publicado: (2016)

Phosphorylation of MCPH1 isoforms during mitosis followed by isoform-specific degradation by APC/C-CDH1
por: Meyer, Stephanie K., et al.
Publicado: (2019)

Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1
por: Nourry, Claire, et al.
Publicado: (2004)

USP7 counteracts SCF(βTrCP)- but not APC(Cdh1)-mediated proteolysis of Claspin
por: Faustrup, Helene, et al.
Publicado: (2009)

Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner
por: Liu, Jia, et al.
Publicado: (2016)

Suppression of APC/C(Cdh1) has subtype specific biological effects in acute myeloid leukemia
por: Ewerth, Daniel, et al.
Publicado: (2016)

Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis
por: Han, Tao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_mdfci5b2v3dqu5h5hhn3uiq3at