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Phosphorylation switches the general splicing repressor SRp38 to a sequence-specific activator
SRp38 is an atypical SR protein that functions as a general splicing repressor when dephosphorylated. We now show that phosphorylated SRp38 functions as a sequence-specific splicing activator. Unlike characterized splicing activators, SRp38 functions in the absence of other SR proteins but requires...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668916/ https://www.ncbi.nlm.nih.gov/pubmed/18794844 http://dx.doi.org/10.1038/nsmb.1485 |