Common Gene Variants in the Tumor Necrosis Factor (TNF) and TNF Receptor Superfamilies and NF-kB Transcription Factors and Non-Hodgkin Lymphoma Risk

BACKGROUND: A promoter polymorphism in the pro-inflammatory cytokine tumor necrosis factor (TNF) (TNF G-308A) is associated with increased non-Hodgkin lymphoma (NHL) risk. The protein product, TNF-α, activates the nuclear factor kappa beta (NF-κB) transcription factor, and is critical for inflammato...

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Detalles Bibliográficos
Autores principales: Wang, Sophia S., Purdue, Mark P., Cerhan, James R., Zheng, Tongzhang, Menashe, Idan, Armstrong, Bruce K., Lan, Qing, Hartge, Patricia, Kricker, Anne, Zhang, Yawei, Morton, Lindsay M., Vajdic, Claire M., Holford, Theodore R., Severson, Richard K., Grulich, Andrew, Leaderer, Brian P., Davis, Scott, Cozen, Wendy, Yeager, Meredith, Chanock, Stephen J., Chatterjee, Nilanjan, Rothman, Nathaniel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669130/
https://www.ncbi.nlm.nih.gov/pubmed/19390683
http://dx.doi.org/10.1371/journal.pone.0005360

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