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A Partial Structural and Functional Rescue of a Retinitis Pigmentosa Model with Compacted DNA Nanoparticles

Previously we have shown that compacted DNA nanoparticles can drive high levels of transgene expression after subretinal injection in the mouse eye. Here we delivered compacted DNA nanoparticles containing a therapeutic gene to the retinas of a mouse model of retinitis pigmentosa. Nanoparticles cont...

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Detalles Bibliográficos
Autores principales:	Cai, Xue, Nash, Zack, Conley, Shannon M., Fliesler, Steven J., Cooper, Mark J., Naash, Muna I.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669177/ https://www.ncbi.nlm.nih.gov/pubmed/19390689 http://dx.doi.org/10.1371/journal.pone.0005290

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