Tor1/Sch9-Regulated Carbon Source Substitution Is as Effective as Calorie Restriction in Life Span Extension

The effect of calorie restriction (CR) on life span extension, demonstrated in organisms ranging from yeast to mice, may involve the down-regulation of pathways, including Tor, Akt, and Ras. Here, we present data suggesting that yeast Tor1 and Sch9 (a homolog of the mammalian kinases Akt and S6K) is...

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Detalles Bibliográficos
Autores principales: Wei, Min, Fabrizio, Paola, Madia, Federica, Hu, Jia, Ge, Huanying, Li, Lei M., Longo, Valter D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669710/
https://www.ncbi.nlm.nih.gov/pubmed/19424415
http://dx.doi.org/10.1371/journal.pgen.1000467

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