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Staged stromal extracellular 3D matrices differentially regulate breast cancer cell responses through PI3K and beta1-integrins
BACKGROUND: Interactions between cancer cells and stroma are critical for growth and invasiveness of epithelial tumors. The biochemical mechanisms behind tumor-stromal interactions leading to increased invasiveness and metastasis are mostly unknown. The goal of this study was to analyze the direct e...
Autores principales: | Castelló-Cros, Remedios, Khan, David R, Simons, Jeffrey, Valianou, Matthildi, Cukierman, Edna |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669806/ https://www.ncbi.nlm.nih.gov/pubmed/19323811 http://dx.doi.org/10.1186/1471-2407-9-94 |
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