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The effects of trastuzumab on the CD4+CD25+FoxP3+ and CD4+IL17A+ T-cell axis in patients with breast cancer

In addition to the direct targeting effects on HER2-positive cells, trastuzumab may have a therapeutic role modulating the activity of the cellular immune system in patients with breast cancer. To investigate this further, the balance of T-regulatory (T(reg)), Th17, natural killer (NK) and NK T (NKT...

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Detalles Bibliográficos
Autores principales:	Horlock, C, Stott, B, Dyson, P J, Morishita, M, Coombes, R C, Savage, P, Stebbing, J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670001/ https://www.ncbi.nlm.nih.gov/pubmed/19277040 http://dx.doi.org/10.1038/sj.bjc.6604963

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