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Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival

Aberrant expression of Eph and ephrin proteins has well-established functions in oncogenesis and tumour progression. We describe EphA1 expression in 6 colorectal cancer (CRC) cell lines, 18 controls and 125 CRC specimens. In addition, a well-characterised cohort of 53 paired normal colon and CRCs wa...

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Detalles Bibliográficos
Autores principales:	Herath, N I, Doecke, J, Spanevello, M D, Leggett, B A, Boyd, A W
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670002/ https://www.ncbi.nlm.nih.gov/pubmed/19277044 http://dx.doi.org/10.1038/sj.bjc.6604970

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