Calnuc plays a role in dynamic distribution of Gαi but not Gβ subunits and modulates ACTH secretion in AtT-20 neuroendocrine secretory cells

In AtT-20 cells ACTH secretion is regulated by both Ca(2+ )and G proteins. We previously demonstrated that calnuc, an EF-hand Ca(2+ )binding protein which regulates Alzheimer's β-amyloid precursor protein (APP) biogenesis, binds both Ca(2+ )as well as Gα subunits. Here we investigate calnuc...

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Detalles Bibliográficos
Autores principales: Lin, Ping, Fischer, Thierry, Lavoie, Christine, Huang, Haining, Farquhar, Marilyn Gist
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670299/
https://www.ncbi.nlm.nih.gov/pubmed/19320978
http://dx.doi.org/10.1186/1750-1326-4-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670299/
https://www.ncbi.nlm.nih.gov/pubmed/19320978
http://dx.doi.org/10.1186/1750-1326-4-15

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