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Calnuc plays a role in dynamic distribution of Gαi but not Gβ subunits and modulates ACTH secretion in AtT-20 neuroendocrine secretory cells
In AtT-20 cells ACTH secretion is regulated by both Ca(2+ )and G proteins. We previously demonstrated that calnuc, an EF-hand Ca(2+ )binding protein which regulates Alzheimer's β-amyloid precursor protein (APP) biogenesis, binds both Ca(2+ )as well as Gα subunits. Here we investigate calnuc...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670299/ https://www.ncbi.nlm.nih.gov/pubmed/19320978 http://dx.doi.org/10.1186/1750-1326-4-15 |