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Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma
BACKGROUND: HAND2, a key regulator for the development of the sympathetic nervous system, is located on chromosome 4q33 in a head-to-head orientation with DEIN, a recently identified novel gene with stage specific expression in primary neuroblastoma (NB). Both genes are expressed in primary NB as we...
Autores principales: | Voth, Harald, Oberthuer, André, Simon, Thorsten, Kahlert, Yvonne, Berthold, Frank, Fischer, Matthias |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670301/ https://www.ncbi.nlm.nih.gov/pubmed/19348682 http://dx.doi.org/10.1186/1471-2199-10-28 |
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