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Extraction and Inhibition of Enzymatic Activity of Botulinum Neurotoxins/A1, /A2, and /A3 by a Panel of Monoclonal Anti-BoNT/A Antibodies

Botulinum neurotoxins (BoNTs) are extremely potent toxins that are capable of causing death or respiratory failure leading to long-term intensive care. Treatment includes serotype-specific antitoxins, which must be administered early in the course of the intoxication. Rapidly determining human expos...

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Detalles Bibliográficos
Autores principales: Kalb, Suzanne R., Lou, Jianlong, Garcia-Rodriguez, Consuelo, Geren, Isin N., Smith, Theresa J., Moura, Hercules, Marks, James D., Smith, Leonard A., Pirkle, James L., Barr, John R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670495/
https://www.ncbi.nlm.nih.gov/pubmed/19399171
http://dx.doi.org/10.1371/journal.pone.0005355