In Vivo Tumor Targeting and Imaging with Engineered Trivalent Antibody Fragments Containing Collagen-Derived Sequences

There is an urgent need to develop new and effective agents for cancer targeting. In this work, a multivalent antibody is characterized in vivo in living animals. The antibody, termed “trimerbody”, comprises a single-chain antibody (scFv) fragment connected to the N-terminal trimerization subdomain...

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Detalles Bibliográficos
Autores principales: Cuesta, Ángel M., Sánchez-Martín, David, Sanz, Laura, Bonet, Jaume, Compte, Marta, Kremer, Leonor, Blanco, Francisco J., Oliva, Baldomero, Álvarez-Vallina, Luis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670539/
https://www.ncbi.nlm.nih.gov/pubmed/19401768
http://dx.doi.org/10.1371/journal.pone.0005381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670539/
https://www.ncbi.nlm.nih.gov/pubmed/19401768
http://dx.doi.org/10.1371/journal.pone.0005381

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