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Local and global modes of drug action in biochemical networks

BACKGROUND: It is becoming increasingly accepted that a shift is needed from the traditional target-based approach of drug development towards an integrated perspective of drug action in biochemical systems. To make this change possible, the interaction networks connecting drug targets to all compon...

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Detalles Bibliográficos
Autores principales: Schwartz, Jean-Marc, Nacher, Jose C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670818/
https://www.ncbi.nlm.nih.gov/pubmed/19351397
http://dx.doi.org/10.1186/1472-6769-9-4