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Mechanisms of Podocyte Injury in Diabetes: Role of Cytochrome P450 and NADPH Oxidases

OBJECTIVE: We investigated the role of cytochrome P450 of the 4A family (CYP4A), its metabolites, and NADPH oxidases both in reactive oxygen species (ROS) production and apoptosis of podocytes exposed to high glucose and in OVE26 mice, a model of type 1 diabetes. RESEARCH DESIGN AND METHODS: Apoptos...

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Detalles Bibliográficos
Autores principales:	Eid, Assaad A., Gorin, Yves, Fagg, Bridget M., Maalouf, Rita, Barnes, Jeffrey L., Block, Karen, Abboud, Hanna E.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671039/ https://www.ncbi.nlm.nih.gov/pubmed/19208908 http://dx.doi.org/10.2337/db08-1536

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