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Cardiovascular Risk Attributable to Diabetes in Southern Brazil: A population-based cohort study
OBJECTIVE: To analyze the effect of diabetes on general and cardiovascular disease (CVD) mortality and morbidity in southern Brazil. RESEARCH DESIGN AND METHODS: A population-based cohort study of 1,091 individuals was conducted. Diabetes was ascertained by medical history. The vital status of 982 i...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671112/ https://www.ncbi.nlm.nih.gov/pubmed/19228861 http://dx.doi.org/10.2337/dc08-1948 |
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author | Moreira, Leila B. Fuchs, Sandra C. Wiehe, Mário Neyeloff, Jeruza L. Picon, Rafael V. Moreira, Marina B. Gus, Miguel Fuchs, Flávio D. |
author_facet | Moreira, Leila B. Fuchs, Sandra C. Wiehe, Mário Neyeloff, Jeruza L. Picon, Rafael V. Moreira, Marina B. Gus, Miguel Fuchs, Flávio D. |
author_sort | Moreira, Leila B. |
collection | PubMed |
description | OBJECTIVE: To analyze the effect of diabetes on general and cardiovascular disease (CVD) mortality and morbidity in southern Brazil. RESEARCH DESIGN AND METHODS: A population-based cohort study of 1,091 individuals was conducted. Diabetes was ascertained by medical history. The vital status of 982 individuals and the incidence of events were ascertained during another visit and through hospital records, death certificates, and verbal necropsy with relatives. RESULTS: The mean ± SD age of participants was 43.1 ± 17 years, and 55.7% were women. The prevalence of diabetes was 4.2%, and the mean follow-up time was 5.3 ± 0.07 years. Mortality was 36.3% and 6.6% in participants with or without diabetes, respectively; the incidence of CVD was 20.8% and 3.0%, with an adjusted hazard ratio of 4.4 (95% CI 2.4–7.9). Diabetic population-attributable risk (PAR) for CVD mortality was 10.1% and 13.1% for total CVD. CONCLUSIONS: Diabetes is responsible for a large PAR for overall mortality and cardiovascular events in Brazil. |
format | Text |
id | pubmed-2671112 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | American Diabetes Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-26711122010-05-01 Cardiovascular Risk Attributable to Diabetes in Southern Brazil: A population-based cohort study Moreira, Leila B. Fuchs, Sandra C. Wiehe, Mário Neyeloff, Jeruza L. Picon, Rafael V. Moreira, Marina B. Gus, Miguel Fuchs, Flávio D. Diabetes Care Original Research OBJECTIVE: To analyze the effect of diabetes on general and cardiovascular disease (CVD) mortality and morbidity in southern Brazil. RESEARCH DESIGN AND METHODS: A population-based cohort study of 1,091 individuals was conducted. Diabetes was ascertained by medical history. The vital status of 982 individuals and the incidence of events were ascertained during another visit and through hospital records, death certificates, and verbal necropsy with relatives. RESULTS: The mean ± SD age of participants was 43.1 ± 17 years, and 55.7% were women. The prevalence of diabetes was 4.2%, and the mean follow-up time was 5.3 ± 0.07 years. Mortality was 36.3% and 6.6% in participants with or without diabetes, respectively; the incidence of CVD was 20.8% and 3.0%, with an adjusted hazard ratio of 4.4 (95% CI 2.4–7.9). Diabetic population-attributable risk (PAR) for CVD mortality was 10.1% and 13.1% for total CVD. CONCLUSIONS: Diabetes is responsible for a large PAR for overall mortality and cardiovascular events in Brazil. American Diabetes Association 2009-05 2009-02-19 /pmc/articles/PMC2671112/ /pubmed/19228861 http://dx.doi.org/10.2337/dc08-1948 Text en © 2009 by the American Diabetes Association. https://creativecommons.org/licenses/by-nc-nd/3.0/Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ (https://creativecommons.org/licenses/by-nc-nd/3.0/) for details. |
spellingShingle | Original Research Moreira, Leila B. Fuchs, Sandra C. Wiehe, Mário Neyeloff, Jeruza L. Picon, Rafael V. Moreira, Marina B. Gus, Miguel Fuchs, Flávio D. Cardiovascular Risk Attributable to Diabetes in Southern Brazil: A population-based cohort study |
title | Cardiovascular Risk Attributable to Diabetes in Southern Brazil: A population-based cohort study |
title_full | Cardiovascular Risk Attributable to Diabetes in Southern Brazil: A population-based cohort study |
title_fullStr | Cardiovascular Risk Attributable to Diabetes in Southern Brazil: A population-based cohort study |
title_full_unstemmed | Cardiovascular Risk Attributable to Diabetes in Southern Brazil: A population-based cohort study |
title_short | Cardiovascular Risk Attributable to Diabetes in Southern Brazil: A population-based cohort study |
title_sort | cardiovascular risk attributable to diabetes in southern brazil: a population-based cohort study |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671112/ https://www.ncbi.nlm.nih.gov/pubmed/19228861 http://dx.doi.org/10.2337/dc08-1948 |
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