Both Strands of siRNA Have Potential to Guide Posttranscriptional Gene Silencing in Mammalian Cells

Despite the widespread application of RNA interference (RNAi) as a research tool for diverse purposes, the key step of strand selection of siRNAs during the formation of RNA-induced silencing complex (RISC) remains poorly understood. Here, using siRNAs targeted to the complementary region of Survivi...

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Detalles Bibliográficos
Autores principales: Wei, Jun-Xia, Yang, Jie, Sun, Ji-Feng, Jia, Lin-Tao, Zhang, Yong, Zhang, Hui-Zhong, Li, Xia, Meng, Yan-Ling, Yao, Li-Bo, Yang, An-Gang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671169/
https://www.ncbi.nlm.nih.gov/pubmed/19401777
http://dx.doi.org/10.1371/journal.pone.0005382

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