Cargando…

Altering Chemosensitivity by Modulating Translation Elongation

BACKGROUND: The process of translation occurs at a nexus point downstream of a number of signal pathways and developmental processes. Modeling activation of the PTEN/AKT/mTOR pathway in the Eμ-Myc mouse is a valuable tool to study tumor genotype/chemosensitivity relationships in vivo. In this model,...

Descripción completa

Detalles Bibliográficos
Autores principales: Robert, Francis, Carrier, Marilyn, Rawe, Svea, Chen, Samuel, Lowe, Scott, Pelletier, Jerry
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671598/
https://www.ncbi.nlm.nih.gov/pubmed/19412536
http://dx.doi.org/10.1371/journal.pone.0005428

Ejemplares similares