CD27(−) B-Cells Produce Class Switched and Somatically Hyper-Mutated Antibodies during Chronic HIV-1 Infection

Class switch recombination and somatic hypermutation occur in mature B-cells in response to antigen stimulation. These processes are crucial for the generation of functional antibodies. During HIV-1 infection, loss of memory B-cells, together with an altered differentiation of naïve B-cells result i...

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Detalles Bibliográficos
Autores principales: Cagigi, Alberto, Du, Likun, Dang, Linh Vu Phuong, Grutzmeier, Sven, Atlas, Ann, Chiodi, Francesca, Pan-Hammarström, Qiang, Nilsson, Anna
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671610/
https://www.ncbi.nlm.nih.gov/pubmed/19412542
http://dx.doi.org/10.1371/journal.pone.0005427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671610/
https://www.ncbi.nlm.nih.gov/pubmed/19412542
http://dx.doi.org/10.1371/journal.pone.0005427

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