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Neuropsychiatric symptoms as a predictor of caregiver burden in Alzheimer’s disease
AIMS: Patients with Alzheimer’s disease need assistance and supervision of their daily activities. They survive for protracted periods of time, placing an extensive burden of care on the caregiver prior to the patient’s death. The present study addressed the predictive value of behavior-related burd...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671738/ https://www.ncbi.nlm.nih.gov/pubmed/19412452 |
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author | Allegri, Ricardo F Sarasola, Diego Serrano, Cecilia M Taragano, Fernando E Arizaga, Raúl L Butman, Judith Loñ, Leandro |
author_facet | Allegri, Ricardo F Sarasola, Diego Serrano, Cecilia M Taragano, Fernando E Arizaga, Raúl L Butman, Judith Loñ, Leandro |
author_sort | Allegri, Ricardo F |
collection | PubMed |
description | AIMS: Patients with Alzheimer’s disease need assistance and supervision of their daily activities. They survive for protracted periods of time, placing an extensive burden of care on the caregiver prior to the patient’s death. The present study addressed the predictive value of behavior-related burden on Alzheimer’s disease caregivers. PARTICIPANTS: 82 patients with probable Alzheimer’s (73.7 ± 8.1 years), and their primary caregivers (59.6 ± 14.8 years, 81.5% women), were assessed. METHODS: Cognitive impairment, neuropsychiatric symptoms, and dementia severity were assessed with Mini Mental State Examination (MMSE), Neuropsychiatric Inventory (NPI), and Clinical Dementia Rating (CDR), respectively. Caregivers were given Zarit’s Burden Interview and Carer Activity Inventory. RESULTS: Neuropsychiatric symptoms like delusions, hallucinations, restlessness, anxiety, euphoria, disinhibition, unusual motor behavior, sleep disturbances, and appetite alterations were the best caregiver burden predictors (NPI r = 0.482, p < 0.001). No correlation with cognition, disease stage, or negative neuropsychiatric symptoms (depression and apathy) was found. CONCLUSION: Increased caregiver burden was related to increased levels of patient behavioral disturbance. Of these symptoms, hallucinations, unusual (motor) behavior, and abnormal behavior at nighttime were the most significant. No correlation with neuropsychiatric symptoms such as apathy and depression was found. This may have relevance to appropriate interventions for caregivers. |
format | Text |
id | pubmed-2671738 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-26717382009-04-30 Neuropsychiatric symptoms as a predictor of caregiver burden in Alzheimer’s disease Allegri, Ricardo F Sarasola, Diego Serrano, Cecilia M Taragano, Fernando E Arizaga, Raúl L Butman, Judith Loñ, Leandro Neuropsychiatr Dis Treat Original Research AIMS: Patients with Alzheimer’s disease need assistance and supervision of their daily activities. They survive for protracted periods of time, placing an extensive burden of care on the caregiver prior to the patient’s death. The present study addressed the predictive value of behavior-related burden on Alzheimer’s disease caregivers. PARTICIPANTS: 82 patients with probable Alzheimer’s (73.7 ± 8.1 years), and their primary caregivers (59.6 ± 14.8 years, 81.5% women), were assessed. METHODS: Cognitive impairment, neuropsychiatric symptoms, and dementia severity were assessed with Mini Mental State Examination (MMSE), Neuropsychiatric Inventory (NPI), and Clinical Dementia Rating (CDR), respectively. Caregivers were given Zarit’s Burden Interview and Carer Activity Inventory. RESULTS: Neuropsychiatric symptoms like delusions, hallucinations, restlessness, anxiety, euphoria, disinhibition, unusual motor behavior, sleep disturbances, and appetite alterations were the best caregiver burden predictors (NPI r = 0.482, p < 0.001). No correlation with cognition, disease stage, or negative neuropsychiatric symptoms (depression and apathy) was found. CONCLUSION: Increased caregiver burden was related to increased levels of patient behavioral disturbance. Of these symptoms, hallucinations, unusual (motor) behavior, and abnormal behavior at nighttime were the most significant. No correlation with neuropsychiatric symptoms such as apathy and depression was found. This may have relevance to appropriate interventions for caregivers. Dove Medical Press 2006-03 /pmc/articles/PMC2671738/ /pubmed/19412452 Text en © 2006 Dove Medical Press Limited. All rights reserved |
spellingShingle | Original Research Allegri, Ricardo F Sarasola, Diego Serrano, Cecilia M Taragano, Fernando E Arizaga, Raúl L Butman, Judith Loñ, Leandro Neuropsychiatric symptoms as a predictor of caregiver burden in Alzheimer’s disease |
title | Neuropsychiatric symptoms as a predictor of caregiver burden in Alzheimer’s disease |
title_full | Neuropsychiatric symptoms as a predictor of caregiver burden in Alzheimer’s disease |
title_fullStr | Neuropsychiatric symptoms as a predictor of caregiver burden in Alzheimer’s disease |
title_full_unstemmed | Neuropsychiatric symptoms as a predictor of caregiver burden in Alzheimer’s disease |
title_short | Neuropsychiatric symptoms as a predictor of caregiver burden in Alzheimer’s disease |
title_sort | neuropsychiatric symptoms as a predictor of caregiver burden in alzheimer’s disease |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671738/ https://www.ncbi.nlm.nih.gov/pubmed/19412452 |
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