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A Vault Nanoparticle Vaccine Induces Protective Mucosal Immunity
BACKGROUND: Generation of robust cell-mediated immune responses at mucosal surfaces while reducing overall inflammation is a primary goal for vaccination. Here we report the use of a recombinant nanoparticle as a vaccine delivery platform against mucosal infections requiring T cell-mediated immunity...
Autores principales: | Champion, Cheryl I., Kickhoefer, Valerie A., Liu, Guangchao, Moniz, Raymond J., Freed, Amanda S., Bergmann, Liisa L., Vaccari, Dana, Raval-Fernandes, Sujna, Chan, Ann M., Rome, Leonard H., Kelly, Kathleen A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671841/ https://www.ncbi.nlm.nih.gov/pubmed/19404403 http://dx.doi.org/10.1371/journal.pone.0005409 |
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