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A systems approach to prion disease

Prions cause transmissible neurodegenerative diseases and replicate by conformational conversion of normal benign forms of prion protein (PrP(C)) to disease-causing PrP(Sc) isoforms. A systems approach to disease postulates that disease arises from perturbation of biological networks in the relevant...

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Detalles Bibliográficos
Autores principales:	Hwang, Daehee, Lee, Inyoul Y, Yoo, Hyuntae, Gehlenborg, Nils, Cho, Ji-Hoon, Petritis, Brianne, Baxter, David, Pitstick, Rose, Young, Rebecca, Spicer, Doug, Price, Nathan D, Hohmann, John G, DeArmond, Stephen J, Carlson, George A, Hood, Leroy E
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671916/ https://www.ncbi.nlm.nih.gov/pubmed/19308092 http://dx.doi.org/10.1038/msb.2009.10

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