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Thyroid Function and Cognition during Aging

We summarize here the studies examining the association between thyroid function and cognitive performance from an aging perspective. The available data suggest that there may be a continuum in which cognitive dysfunction can result from increased or decreased concentrations of thyroid hormones. Cli...

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Detalles Bibliográficos
Autores principales: Bégin, M. E., Langlois, M. F., Lorrain, D., Cunnane, S. C.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671998/
https://www.ncbi.nlm.nih.gov/pubmed/19415145
http://dx.doi.org/10.1155/2008/474868
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author Bégin, M. E.
Langlois, M. F.
Lorrain, D.
Cunnane, S. C.
author_facet Bégin, M. E.
Langlois, M. F.
Lorrain, D.
Cunnane, S. C.
author_sort Bégin, M. E.
collection PubMed
description We summarize here the studies examining the association between thyroid function and cognitive performance from an aging perspective. The available data suggest that there may be a continuum in which cognitive dysfunction can result from increased or decreased concentrations of thyroid hormones. Clinical and subclinical hypothyroidism as well as hyperthyroidism in middle-aged and elderly adults are both associated with decreased cognitive functioning, especially memory, visuospatial organization, attention, and reaction time. Mild variations of thyroid function, even within normal limits, can have significant consequences for cognitive function in the elderly. Different cognitive deficits possibly related to thyroid failure do not necessarily follow a consistent pattern, and L-thyroxine treatment may not always completely restore normal functioning in patients with hypothyroidism. There is little or no consensus in the literature regarding how thyroid function is associated with cognitive performance in the elderly.
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spelling pubmed-26719982009-05-04 Thyroid Function and Cognition during Aging Bégin, M. E. Langlois, M. F. Lorrain, D. Cunnane, S. C. Curr Gerontol Geriatr Res Review Article We summarize here the studies examining the association between thyroid function and cognitive performance from an aging perspective. The available data suggest that there may be a continuum in which cognitive dysfunction can result from increased or decreased concentrations of thyroid hormones. Clinical and subclinical hypothyroidism as well as hyperthyroidism in middle-aged and elderly adults are both associated with decreased cognitive functioning, especially memory, visuospatial organization, attention, and reaction time. Mild variations of thyroid function, even within normal limits, can have significant consequences for cognitive function in the elderly. Different cognitive deficits possibly related to thyroid failure do not necessarily follow a consistent pattern, and L-thyroxine treatment may not always completely restore normal functioning in patients with hypothyroidism. There is little or no consensus in the literature regarding how thyroid function is associated with cognitive performance in the elderly. Hindawi Publishing Corporation 2008 2008-09-01 /pmc/articles/PMC2671998/ /pubmed/19415145 http://dx.doi.org/10.1155/2008/474868 Text en Copyright © 2008 M. E. Bégin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Bégin, M. E.
Langlois, M. F.
Lorrain, D.
Cunnane, S. C.
Thyroid Function and Cognition during Aging
title Thyroid Function and Cognition during Aging
title_full Thyroid Function and Cognition during Aging
title_fullStr Thyroid Function and Cognition during Aging
title_full_unstemmed Thyroid Function and Cognition during Aging
title_short Thyroid Function and Cognition during Aging
title_sort thyroid function and cognition during aging
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671998/
https://www.ncbi.nlm.nih.gov/pubmed/19415145
http://dx.doi.org/10.1155/2008/474868
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