Cargando…

Molecular Pathology of Human Prion Diseases

Prion diseases are fatal neurodegenerative conditions in humans and animals. In this review, we summarize the molecular background of phenotypic variability, relation of prion protein (PrP) to other proteins associated with neurodegenerative diseases, and pathogenesis of neuronal vulnerability. PrP...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kovacs, Gabor G., Budka, Herbert
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2009
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672014/ https://www.ncbi.nlm.nih.gov/pubmed/19399233 http://dx.doi.org/10.3390/ijms10030976

Ejemplares similares

Genesis of Mammalian Prions: From Non-infectious Amyloid Fibrils to a Transmissible Prion Disease
por: Makarava, Natallia, et al.
Publicado: (2011)

Recombinant prion protein induces a new transmissible prion disease in wild-type animals
por: Makarava, Natallia, et al.
Publicado: (2010)

Molecular pathology of human prion disease
por: Wadsworth, Jonathan D. F., et al.
Publicado: (2010)

Fatal Prion Disease in a Mouse Model of Genetic E200K Creutzfeldt-Jakob Disease
por: Friedman-Levi, Yael, et al.
Publicado: (2011)

Correction: Fatal Prion Disease in a Mouse Model of Genetic E200K Creutzfeldt-Jakob Disease
por: Friedman-Levi, Yael, et al.
Publicado: (2017)

Molecular Pathological Classification of Neurodegenerative Diseases: Turning towards Precision Medicine
por: Kovacs, Gabor G.
Publicado: (2016)

Sporadic Creutzfeldt-Jakob disease VM1: phenotypic and molecular characterization of a novel subtype of human prion disease
por: Gelpi, Ellen, et al.
Publicado: (2022)

Targeting of prion-infected lymphoid cells to the central nervous system accelerates prion infection
por: Friedman-Levi, Yael, et al.
Publicado: (2012)

Tau pathology in Creutzfeldt‐Jakob disease revisited
por: Kovacs, Gabor G., et al.
Publicado: (2016)

Heterogeneity and Architecture of Pathological Prion Protein Assemblies: Time to Revisit the Molecular Basis of the Prion Replication Process?
por: Igel-Egalon, Angélique, et al.
Publicado: (2019)

Prion replication environment defines the fate of prion strain adaptation
por: Katorcha, Elizaveta, et al.
Publicado: (2018)

Anti-Prion Systems Block Prion Transmission, Attenuate Prion Generation, Cure Most Prions as They Arise and Limit Prion-Induced Pathology in Saccharomyces cerevisiae
por: Wickner, Reed B., et al.
Publicado: (2022)

The Role of the NADPH Oxidase NOX2 in Prion Pathogenesis
por: Sorce, Silvia, et al.
Publicado: (2014)

Molecular pathogenesis of sporadic prion diseases in man
por: Safar, Jiri G.
Publicado: (2012)

An overview of human prion diseases
por: Imran, Muhammad, et al.
Publicado: (2011)

Excretion of Transmissible Spongiform Encephalopathy Infectivity in Urine
por: Gregori, Luisa, et al.
Publicado: (2008)

Histotype-Dependent Oligodendroglial PrP Pathology in Sporadic CJD: A Frequent Feature of the M2C “Strain”
por: Gelpi, Ellen, et al.
Publicado: (2021)

Cellular Prion Protein: From Physiology to Pathology
por: Yusa, Sei-ichi, et al.
Publicado: (2012)

Prion Diseases of Humans and Animals
por: Esiri, Margaret
Publicado: (1994)

Human prion diseases and the prion protein – what is the current state of knowledge?
por: Nafe, Reinhold, et al.
Publicado: (2023)

Co‐incidental C9orf72 expansion mutation‐related frontotemporal lobar degeneration pathology and sporadic Creutzfeldt−Jakob disease
por: Klotz, Sigrid, et al.
Publicado: (2020)

Genetic Studies in Human Prion Diseases
por: Jeong, Byung-Hoon, et al.
Publicado: (2014)

Kuru, the First Human Prion Disease †
por: Liberski, Paweł P., et al.
Publicado: (2019)

Medial Temporal Lobe Involvement in Human Prion Diseases: Implications for the Study of Focal Non Prion Neurodegenerative Pathology
por: Rábano, Alberto, et al.
Publicado: (2021)

Accumulation of prion protein in the vagus nerve in creutzfeldt–jakob disease
por: Kresl, Philip, et al.
Publicado: (2019)

The prion-like phenomenon in Alzheimer’s disease: Evidence of pathology transmission in humans
por: Gomez-Gutierrez, Ruben, et al.
Publicado: (2020)

Prions and Prion Diseases: Current Perspectives
por: Belay, Ermias D.
Publicado: (2004)

On the role of the cellular prion protein in the uptake and signaling of pathological aggregates in neurodegenerative diseases
por: Legname, Giuseppe, et al.
Publicado: (2020)

Prevalence of mixed pathologies in the aging brain
por: Rahimi, Jasmin, et al.
Publicado: (2014)

Prion and Prion-Like Protein Strains: Deciphering the Molecular Basis of Heterogeneity in Neurodegeneration
por: Scialò, Carlo, et al.
Publicado: (2019)

Epidemiological characteristics of human prion diseases
por: Chen, Cao, et al.
Publicado: (2016)

Differential overexpression of SERPINA3 in human prion diseases
por: Vanni, S., et al.
Publicado: (2017)

Establishment of a Special Platform for the Research of Prion and the Diagnosis of Human Prion Disease — China’s Studies
por: Xiao, Kang, et al.
Publicado: (2022)

Differential Interactions of Molecular Chaperones and Yeast Prions
por: Barbitoff, Yury A., et al.
Publicado: (2022)

Molecular Model of Prion Transmission to Humans
por: Jones, Michael, et al.
Publicado: (2009)

Molecular Modeling of Prion Transmission to Humans
por: Levavasseur, Etienne, et al.
Publicado: (2014)

Metal Dyshomeostasis and Their Pathological Role in Prion and Prion-Like Diseases: The Basis for a Nutritional Approach
por: Toni, Mattia, et al.
Publicado: (2017)

Prion and Prion-like Diseases in Humans: Poster Abstracts
Publicado: (2013)

Human Prion Diseases
por: Esiri, Margaret M
Publicado: (1993)

Redox mechanisms and their pathological role in prion diseases: The road to ruin
por: Spiers, Jereme G., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_n1k9ggse2cg23cfidongjcuepk