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Origin of Homochirality in Biosystems

Experimental data for a series of central and simple molecules in biosystems show that some amino acids and a simple sugar molecule have a chiral discrimination in favor of homochirality. Models for segregation of racemic mixtures of chiral amphiphiles and lipophiles in aqueous solutions show that t...

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Detalles Bibliográficos
Autor principal: Toxvaerd, Søren
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672030/
https://www.ncbi.nlm.nih.gov/pubmed/19399249
http://dx.doi.org/10.3390/ijms10031290
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author Toxvaerd, Søren
author_facet Toxvaerd, Søren
author_sort Toxvaerd, Søren
collection PubMed
description Experimental data for a series of central and simple molecules in biosystems show that some amino acids and a simple sugar molecule have a chiral discrimination in favor of homochirality. Models for segregation of racemic mixtures of chiral amphiphiles and lipophiles in aqueous solutions show that the amphiphiles with an active isomerization kinetics can perform a spontaneous break of symmetry during the segregation and self-assembly to homochiral matter. Based on this observation it is argued that biomolecules with a sufficiently strong chiral discrimination could be the origin of homochirality in biological systems.
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spelling pubmed-26720302009-04-27 Origin of Homochirality in Biosystems Toxvaerd, Søren Int J Mol Sci Article Experimental data for a series of central and simple molecules in biosystems show that some amino acids and a simple sugar molecule have a chiral discrimination in favor of homochirality. Models for segregation of racemic mixtures of chiral amphiphiles and lipophiles in aqueous solutions show that the amphiphiles with an active isomerization kinetics can perform a spontaneous break of symmetry during the segregation and self-assembly to homochiral matter. Based on this observation it is argued that biomolecules with a sufficiently strong chiral discrimination could be the origin of homochirality in biological systems. Molecular Diversity Preservation International (MDPI) 2009-03-18 /pmc/articles/PMC2672030/ /pubmed/19399249 http://dx.doi.org/10.3390/ijms10031290 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Toxvaerd, Søren
Origin of Homochirality in Biosystems
title Origin of Homochirality in Biosystems
title_full Origin of Homochirality in Biosystems
title_fullStr Origin of Homochirality in Biosystems
title_full_unstemmed Origin of Homochirality in Biosystems
title_short Origin of Homochirality in Biosystems
title_sort origin of homochirality in biosystems
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672030/
https://www.ncbi.nlm.nih.gov/pubmed/19399249
http://dx.doi.org/10.3390/ijms10031290
work_keys_str_mv AT toxvaerdsøren originofhomochiralityinbiosystems