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Origin of Homochirality in Biosystems
Experimental data for a series of central and simple molecules in biosystems show that some amino acids and a simple sugar molecule have a chiral discrimination in favor of homochirality. Models for segregation of racemic mixtures of chiral amphiphiles and lipophiles in aqueous solutions show that t...
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Formato: | Texto |
Lenguaje: | English |
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Molecular Diversity Preservation International (MDPI)
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672030/ https://www.ncbi.nlm.nih.gov/pubmed/19399249 http://dx.doi.org/10.3390/ijms10031290 |
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author | Toxvaerd, Søren |
author_facet | Toxvaerd, Søren |
author_sort | Toxvaerd, Søren |
collection | PubMed |
description | Experimental data for a series of central and simple molecules in biosystems show that some amino acids and a simple sugar molecule have a chiral discrimination in favor of homochirality. Models for segregation of racemic mixtures of chiral amphiphiles and lipophiles in aqueous solutions show that the amphiphiles with an active isomerization kinetics can perform a spontaneous break of symmetry during the segregation and self-assembly to homochiral matter. Based on this observation it is argued that biomolecules with a sufficiently strong chiral discrimination could be the origin of homochirality in biological systems. |
format | Text |
id | pubmed-2672030 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Molecular Diversity Preservation International (MDPI) |
record_format | MEDLINE/PubMed |
spelling | pubmed-26720302009-04-27 Origin of Homochirality in Biosystems Toxvaerd, Søren Int J Mol Sci Article Experimental data for a series of central and simple molecules in biosystems show that some amino acids and a simple sugar molecule have a chiral discrimination in favor of homochirality. Models for segregation of racemic mixtures of chiral amphiphiles and lipophiles in aqueous solutions show that the amphiphiles with an active isomerization kinetics can perform a spontaneous break of symmetry during the segregation and self-assembly to homochiral matter. Based on this observation it is argued that biomolecules with a sufficiently strong chiral discrimination could be the origin of homochirality in biological systems. Molecular Diversity Preservation International (MDPI) 2009-03-18 /pmc/articles/PMC2672030/ /pubmed/19399249 http://dx.doi.org/10.3390/ijms10031290 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Toxvaerd, Søren Origin of Homochirality in Biosystems |
title | Origin of Homochirality in Biosystems |
title_full | Origin of Homochirality in Biosystems |
title_fullStr | Origin of Homochirality in Biosystems |
title_full_unstemmed | Origin of Homochirality in Biosystems |
title_short | Origin of Homochirality in Biosystems |
title_sort | origin of homochirality in biosystems |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672030/ https://www.ncbi.nlm.nih.gov/pubmed/19399249 http://dx.doi.org/10.3390/ijms10031290 |
work_keys_str_mv | AT toxvaerdsøren originofhomochiralityinbiosystems |