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Molecular Pathogenesis of Alzheimer’s Disease: Reductionist versus Expansionist Approaches

Alzheimer’s disease (AD) is characterized clinically by dementia and pathologically by two hallmark lesions, senile plaques and neurofibrillary tangles. About a quarter century ago these hallmark lesions were purified and their protein constituents identified, precipitating an avalanche of molecular...

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Detalles Bibliográficos
Autores principales:	Castellani, Rudy J., Zhu, Xiongwei, Lee, Hyoung-Gon, Smith, Mark A., Perry, George
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2009
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672036/ https://www.ncbi.nlm.nih.gov/pubmed/19399255 http://dx.doi.org/10.3390/ijms10031386

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