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Release of 11-cis-retinal from cellular retinaldehyde-binding protein by acidic lipids

PURPOSE: To determine molecular mechanisms for the release of 11-cis-retinal from the binding pocket of cellular retinaldehyde-binding protein (CRALBP). METHODS: Binding of CRALBP to lipid surfaces was assessed with a lipid-immunoblot assay. Lipids were presented to CRALBP as small unilamellar vesic...

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Detalles Bibliográficos
Autores principales: Saari, John C., Nawrot, Maria, Stenkamp, Ronald E., Teller, David C., Garwin, Gregory G.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672148/
https://www.ncbi.nlm.nih.gov/pubmed/19390642