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The management of gestational diabetes

The incidence of gestational diabetes is increasing. As gestational diabetes is associated with adverse pregnancy outcomes, and has long-term implications for both mother and child, it is important that it is recognized and appropriately managed. This review will examine the pharmacological options...

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Detalles Bibliográficos
Autor principal: Cheung, N Wah
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672462/
https://www.ncbi.nlm.nih.gov/pubmed/19436673
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author Cheung, N Wah
author_facet Cheung, N Wah
author_sort Cheung, N Wah
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description The incidence of gestational diabetes is increasing. As gestational diabetes is associated with adverse pregnancy outcomes, and has long-term implications for both mother and child, it is important that it is recognized and appropriately managed. This review will examine the pharmacological options for the management of gestational diabetes, as well as the evidence for blood glucose monitoring, dietary and exercise therapy. The medical management of gestational diabetes is still evolving, and recent randomized controlled trials have added considerably to our knowledge in this area. As insulin therapy is effective and safe, it is considered the gold standard of pharmacotherapy for gestational diabetes, against which other treatments have been compared. The current experience is that the short acting insulin analogs lispro and aspart are safe, but there are only limited data to support the use of long acting insulin analogs. There are randomized controlled trials which have demonstrated efficacy of the oral agents glyburide and metformin. Whilst short-term data have not demonstrated adverse effects of glyburide and metformin on the fetus, and they are increasingly being used in pregnancy, there remain long-term concerns regarding their potential for harm.
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spelling pubmed-26724622009-08-08 The management of gestational diabetes Cheung, N Wah Vasc Health Risk Manag Review The incidence of gestational diabetes is increasing. As gestational diabetes is associated with adverse pregnancy outcomes, and has long-term implications for both mother and child, it is important that it is recognized and appropriately managed. This review will examine the pharmacological options for the management of gestational diabetes, as well as the evidence for blood glucose monitoring, dietary and exercise therapy. The medical management of gestational diabetes is still evolving, and recent randomized controlled trials have added considerably to our knowledge in this area. As insulin therapy is effective and safe, it is considered the gold standard of pharmacotherapy for gestational diabetes, against which other treatments have been compared. The current experience is that the short acting insulin analogs lispro and aspart are safe, but there are only limited data to support the use of long acting insulin analogs. There are randomized controlled trials which have demonstrated efficacy of the oral agents glyburide and metformin. Whilst short-term data have not demonstrated adverse effects of glyburide and metformin on the fetus, and they are increasingly being used in pregnancy, there remain long-term concerns regarding their potential for harm. Dove Medical Press 2009 2009-04-08 /pmc/articles/PMC2672462/ /pubmed/19436673 Text en © 2009 Dove Medical Press Limited. All rights reserved
spellingShingle Review
Cheung, N Wah
The management of gestational diabetes
title The management of gestational diabetes
title_full The management of gestational diabetes
title_fullStr The management of gestational diabetes
title_full_unstemmed The management of gestational diabetes
title_short The management of gestational diabetes
title_sort management of gestational diabetes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672462/
https://www.ncbi.nlm.nih.gov/pubmed/19436673
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