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Type I Interferons and Interferon Regulatory Factors Regulate TNF-Related Apoptosis-Inducing Ligand (TRAIL) in HIV-1-Infected Macrophages

TNF-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family that participates in HIV-1 pathogenesis through the depletion of CD4+ T cells. TRAIL is expressed on the cell membrane of peripheral immune cells and can be cleaved into a soluble, secreted form. The regulation of TRAIL in m...

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Detalles Bibliográficos
Autores principales:	Huang, Yunlong, Walstrom, Angelique, Zhang, Luwen, Zhao, Yong, Cui, Min, Ye, Ling, Zheng, Jialin C.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672636/ https://www.ncbi.nlm.nih.gov/pubmed/19404407 http://dx.doi.org/10.1371/journal.pone.0005397

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